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Herein, we specifically comment on some literary works evidences, which connect the food-derived antioxidants and metal-chelating representatives with therapy and prevention of oxidative tension and irritation that play a key part into the progression of COVID-19. USEFUL APPLICATIONS Oxidative stress and infection are fundamental facets increasing COVID-19 severity particularly in the existence of persistent diseases from the anti-oxidant system fragility. These evidences support the sugge