https://www.selleckchem.com/pr....oducts/2-3-cgamp.htm
Nanobodies are popular and versatile tools for structural biology. They have a compact single immunoglobulin domain organization, bind target proteins with high affinities while reducing their conformational heterogeneity and stabilize multi-protein complexes. Here we demonstrate that engineered nanobodies can also help overcome two major obstacles that limit the resolution of single-particle cryo-electron microscopy reconstructions particle size and preferential orientation at the water-air interfaces. We have developed and character
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