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In the validation cohort, no CNVs for MUC2 or MUC5B had been identified. Nonetheless, in the event group, 36.21% of individuals had a duplication of MUC5AC, and 28.03% of controls had MUC5AC replication (χ2 = 9.123; p = 0.0025). The association of MUC5AC copy number with AR ended up being significant in a multivariable logistic regression after adjusting for age and intercourse (Padj = 0.0010; OR = 2.073; 95% CI, 1.625-2.805). Real-time PCR validation confirmed replication of MUC5AC, while the CNV g
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