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Noise exposure (NE) has been recognized as one of the causes of sensorineural hearing loss (SNHL); which can bring about irreversible damage to sensory hair cells in the cochlea, through the launch of oxidative stress pathways and inflammation. Accordingly, determining molecular mechanism involved in regulating hair cell apoptosis via NE is essential to prevent hair cell damage. However, the role of microRNAs (miRNAs) in degeneration of sensory cells of the cochlea during NE has not been so far uncovered. Thus, the main purpose of this