https://www.selleckchem.com/products/tas4464.html
Aminoglycosides are widely known for their ototoxic side effects. Nevertheless, they are potent antibiotics used in the treatment of life-threatening conditions because of the current concern for antibiotic resistance. We hypothesized that creatine supplements which are believed to improve mitochondrial antioxidant defense system and maintain optimal energy homeostasis may improve the ototoxic side effects. This study aimed to investigate the protective effects of creatine monohydrate against ototoxicity induced by amikacin in rats in a
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