https://www.selleckchem.com/pr....oducts/3-deazaneplan
BACKGROUND Pulmonary fibrosis is a respiratory disease caused by the proliferation of fibroblasts and accumulation of the extracellular matrix (ECM). It is known that the lung ECM is mainly composed of a three-dimensional fiber mesh filled with various high-molecular-weight proteins. However, the small-molecular-weight proteins in the lung ECM and their differences between normal and fibrotic lung ECM are largely unknown. METHODS Healthy adult male Sprague-Dawley rats (Rattus norvegicus) weighing about 150 to 200 g wer