https://www.selleckchem.com/pr....oducts/opicapone.htm
OR [95%CI, 95% confidence interval] per doubling NT-proBNP 1.26 [1.07-1.49]; per 10 mL/min/1.73 m2 eGFR decrease 1.16 [1.03-1.31]). Higher loop diuretic doses, lower aldosterone antagonist doses, and higher eGFR predicted WRF (furosemide per 40 mg increase 1.32 [1.08-1.62]; spironolactone per 25 mg decrease 1.76 [1.07-2.89]; per 10 mL/min/1.73 m2 eGFR increase 1.40 [1.20-1.63]). WRF and higher rank of tubular injury individually entailed higher risk of the composite endpoint (adjusted hazard ratios, adj. HR [95%CI] WRF 1.9 [1.1-3.4],
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