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7% (95% CI 19-45.1)). Overall, the endovascular treated patients faced more than 50% increased risk of major amputation or death compared to that of a vein bypass, after adjusting for co-morbidity and TASC-classification (HR 1.56 (95% CI 1.21-2.05)). As expected, postoperative complications, length of hospital stay (LOS) and reinterventions were more frequent in the bypass groups. CONCLUSION In this non-randomized study, autologous vein bypass was superior to both PTA/S and synthetic bypass in regard to amputation free survival and overall