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Right here, we blended numerous ways to analyze the hereditary alterations in 86 colorectal adenomas (including 35 sessile serrated lesions, 15 conventional adenomas and 36 standard adenomatous polyps). We also investigated the in vitro plus in vivo oncogenic properties of a novel variant associated with NCOA4-RET fusion gene. Molecular profiling disclosed that sessile serrated lesions and old-fashioned serrated adenomas have actually distinct clinicopathological and molecular functio
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