https://www.selleckchem.com/products/mmaf.html
(1) Background Colorectal cancer (CRC) is among the best examples of the relationship between inflammation and increased cancer risk. (2) Methods To examine the effects of spontaneous low-grade chronic inflammation on the pathogenesis of CRC, we developed a new murine model of colitis-associated cancer (CAC) by crossing Mucin 2 mutated mice (Winnie) with ApcMin/+ mice. (3) Results The resulting Winnie-ApcMin/+ model combines an inflammatory background with a genetic predisposition to small intestinal polyposis. Winnie-ApcMin/+ mice show an
Like
Comment
Share
