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FI's categorical important factors had been analyzed. Spearman correlation coefficient ( Fifty RCTs with 120 outcomes in 7869 clients were included. The FI distribution ended up being irregular with median 3 (interquartile range 1-7, P = 0.0001). The FIs and robustness were suffering from positive results of interest, various client populations, and treatments (T = 18.215,16.667, 23.107; P = 0.02,0.0001, 0.001, correspondingly). A cubic relationship between the FIs