https://www.selleckchem.com/pr....oducts/XL765(SAR2454
The total and outer retinal thicknesses were lower on average after 11 months and 7 months in SOD1 KO mice compared with age-matched controls. Neovascularizations were found in one out of seven KO animals. OCT imaging proved beneficial for a detailed in vivo characterization of the pathological changes in SOD1 KO mice. Phenotyping of animal models using modern imaging concepts can be conducted with more precision and might also ease the translation of conclusions between clinical and preclinical research. Phenotyping of animal
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