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g., phenylalanine) show extreme values of minor groove width as well. For a number of hydrophobic amino acids, distinct additional structure preferences might be identified for deposits getting together with the widened DNA small groove. These outcomes hold even with discarding the essential populous categories of minor groove-binding proteins.The oxidative damage of this retinal pigment epithelium (RPE) may be the early event that underlies the pathogenesis of maculopathies. Num