https://www.selleckchem.com/products/azd9291.html
In the diabetic retina of mice, the morphological damage was alleviated by piperine. Likewise, the retinal vascular leakage was substantially decreased by piperine. Further, the protein levels of HIF-1α and VEGFA were significantly reduced by piperine. Moreover, the level of the antiangiogenic factor of PEDF dramatically increased by piperine. Piperine may exert protective effects on the retina of mice with diabetes regulating the pro-antiangiogenic homeostasis composed of HIF-1/VEGFA and PEDF. Piperine may exert protective effects on t
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