https://www.selleckchem.com/pr....oducts/Bafetinib.htm
We show that the ESP is accurate under several realistic sampling protocols and we prove analytically that it can at least double the best precision achievable by standard approaches. We generalise the ESP to incorporate phylogenetic uncertainty in a new Bayesian package (BESP) in BEAST2. We re-examine two well-studied empirical datasets from virus epidemiology and molecular evolution and find that the BESP improves upon previous coalescent estimators and generates new, biologically-useful insights into the sampling protocols underpin