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This work is aimed to investigate the effect of research and development (RD) on reduce in environmental pressures through an empirical analysis of the top six global carbon emitters (the C6 China, USA, India, Russia, Japan, and Germany). This work is valuable toward carbon reduction within C6 countries and the world (C6 emit roughly 60% of the global carbon emissions). Moreover, it is also meaningful for exploring the decoupling of economic development from carbon emissions in other areas (both developing and developed countries).