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circumventing the requirement of feeding expensive ingredients). Biosynthesis of fluoronucleotides and fluorosugars in designed P. putida is shown with mineral fluoride both as only fluorine source (i.e. substrate of the pathway) and also as inducer regarding the artificial circuit. This process expands the chemical landscape of mobile industrial facilities by providing alternate biosynthetic strategies towards fluorinated building-blocks.Engineered RNA elements are automated tools effective at finding little molecules,