https://www.selleckchem.com/pr....oducts/idasanutlin-r
Background Accumulating evidence proposed JAK inhibitors as therapeutic targets warranting rapid investigation. Objective This study evaluated the efficacy and safety of ruxolitinib, a Janus-associated kinase (JAK1/2) inhibitor, for COVID-19. Methods We conducted a prospective, multicenter, single-blind, randomized controlled phase II trial involving patients with severe COVID-19. Results Forty-three patients were randomly assigned (11) to receive ruxolitinib plus SoC treatment (22 patients) or placebo based on SoC treatment
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