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Moreover, these conformational changes disrupted the interactive regions and binding affinities of lncRNA-HCG23 and TF-E2F6, suggesting that these may represent regulatory mechanisms in lung diseases. Taken together, our findings support that SNP-induced changes in lncRNA conformations regulate many biological processes, providing novel insight into the role of the lncRNA "structurome" in human diseases. Copyright © 2020 Lu, Ding, Bai, Li, Zhang, Wang, Gao, Xu and Wang.When a cell divides into two daughter cells, the total cell surface a
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