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Introduction Motor neuron disease (MND) is a progressive neuromuscular disorder that can have significant and debilitating impact on the affected patient and families. Spouses are the primary carers for persons with MND in India, and the life of the person with MND and their spouse is never the same after the diagnosis. Aim The objective was to explore the lived experience of spouses of persons diagnosed with MND. Methods A qualitative exploratory study with three-point interviews was conducted with spouse caregivers of two persons diag