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In the present examination, the main reason for picking cholic acid while the important scaffold lies in the reality that this has a facially amphiphilic nature, which offers ample opportunity to improve the amphiphilicity by connecting the amino acid lysine. A total of 16 book amphipathic cholic acid types had been synthesized by sequentially linking lysine to C3-β-amino cholic acid methyl ester to maintain the hydrophobic/hydrophilic balance, that could
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