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To investigate the prevalence of primary aldosteronism (PA) among participants with hypertension, evaluate the concordance of PA classification between adrenal computed tomography and adrenal venous sampling, and compare the outcomes of surgery and medication for unilateral PA. A prospective study was conducted among all inpatients with hypertension (n= 7594) at the National Center for Cardiovascular Diseases, China, from May 2016 to April 2018. Of the 7594 participants, 8.12% (n= 617) with plasma aldosterone-renin ratio ≥3.7 were poss