https://www.selleckchem.com/pr....oducts/bupivacaine.h
The insulin-degrading enzyme (IDE) is a metalloendopeptidase with a high affinity for insulin. Human genetic polymorphisms in Ide have been linked to increased risk for T2DM. In mice, hepatic Ide ablation causes glucose intolerance and insulin resistance when mice are fed a regular diet. These studies were undertaken to further investigate its regulatory role in glucose homeostasis and insulin sensitivity in diet-induced obesity. To this end, we have compared the metabolic effects of loss versus gain of IDE function in mice fed a hi
Like
Comment
Share
