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To conclude, lycopene can affect the expression of relevant genes, and this might be one of the reasons that lycopene can regulate fat metabolism. © 2020 Blackwell Verlag GmbH.ET-26 hydrochloride (ET-26HCl), a novel analog of etomidate, induces as efficient sedation, with good cardiac and breathing stability, as etomidate but with mild adrenocortical suppression. The objective of this research would be to evaluate the possible negative effects of ET-26HCl in rats. In a single-dose toxicity stud