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Passively obtained maternal GBS-specific antibodies protect newborns from early-onset illness, yet their particular impact on GI colonization and LO infection is unexplored. Making use of murine different types of both perinatal and postnatal GBS acquisition, we assessed the kinetics of GBS GI colonization, progression to unpleasant disease, while the part of GBS-specific IgG production in uncovered offspring and juvenile mi