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The present systematic meta-analysis is an effort to assess the impact of NOSES, namely, its oncological effects and medical safety in colorectal disease patients. Pooled reviews revealed that NOSES was more advanced than LAP surgery with regards to postoperative morbidity, postoperative pain, medical center stay, the full time to first flatus, cosmetic outcomes, and wound infections; nevertheless, NOSES ended up being involving a longer operative time. Thinking about the abovementioned limitations as well as the