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Ibuprofen, carbamazepine, and caffeine contributed most to the risk quotients. The current work highlights that micro-estuary ecosystems, like the Alexander estuary, are continuously exposed to pharmaceuticals and most likely to other pollutants, placing these ecologically important systems under an elevated risk in comparison to the more frequently studied large estuarine systems.Curved π-electronic molecules, dipyrrolylbenzodiazepines (dpbs), were synthesized via condensation of 1,3-dipyrrolyldiketones and phenylenediamines. Dpbs exhi