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Double-fertilization in angiosperms requires precise communication between the male gametophyte (pollen), the female tissues, and the associated female gametophyte (embryo sac) to facilitate efficient fertilization. Numerous small molecules, proteins, and peptides have been shown to impact double-fertilization through the disruption of pollen germination, pollen tube growth, pollen tube guidance, or pollen tube penetration of the female tissues. The genetic basis of signaling events that lead to successful double-fertilization has been g