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5%. In a patient study, Gadovist increased the Dmean for brain, HN, and lung cancer patients by 0.65-8.9%. The dose variation due to Gadovist grew large in the low-dose region in HN and lung cancer. The GTV dose variation due to Gadovist in all treatment site was below 2% at 0-3 T if the Gadovist concentration was lower than 0.2 mmol/ml-1.Di-(2-ethylhexyl) phthalate has been reported to interfere with the development and function of animal reproductive systems. However, hardly any studies provide methods to minimize or prevent