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To assess psychosocial risk factors for increased emergency hospital utilization by sickle cell patients. Emergency hospital utilization by sickle cell disease patients is high but heterogeneous between patients and in a given patient over time. Psychosocial factors affect emergency hospital utilization and are a possible target to improve the management of sickle cell disease. This review will include all original quantitative studies evaluating the impact of psychosocial risk factors on emergency hospital utilization by sickle cel