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Furthermore, EJ cells were notably blocked in G0/G1 phase, in comparison to the blank control group (p less then 0.05). In inclusion, PIC enhanced apoptosis of EJ cells in a concentration-dependent fashion (p less then 0.05). Results from western blotting showed that, in contrast to the control group, PIC upregulated the protein phrase of PTEN, but downregulated Akt protein phosphorylation, in accordance with control cells. picture substantially prevents the proliferation of EJ