https://www.selleckchem.com/pr....oducts/pilaralisib-x
RESULTS 42 differentially spliced activated platelet-specific RNA transcripts in 34 genes were altered in CFP from fTBI patients (both upregulated and downregulated). CONCLUSIONS We have discovered differentially-expressed activated platelet-specific spliced RNA transcripts present in CFP from isolated severe fatal TBI patients that are up- or downregulated compared to minimally-injured trauma controls. This proof-of-concept suggests that a pool of immature platelet RNAs undergo splicing events after injury for presumed modula