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ADHD Medications For Adults Stimulants are able to regulate the levels of chemical messengers that regulate attention in the brain. They are first-line medications for treating ADHD. They aren't thought to be habit-forming, however they can have side effects, such as headaches and sleep problems. Your doctor could also prescribe guanfacine (brand names Tenex and Intuniv) or Clonidine (Catapres) to decrease hyperactivity and impulsivity. These drugs have a longer duration of