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Two of the alternative methods require a second baseline measurement with the same PROM or another correlated PROM. The third method involves the construction of two parallel tests based on splitting the PROM's item set. Two methods could be applied to the real data. MIC baseline dependency should not be tested in subgroups based on stratification on the baseline PROM score. Instead, one or more of the suggested alternative methods should be used. MIC baseline dependency should not be tested in subgroups based on stratification on the
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