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In women with a cervical length less then 25 mm, vaginal progesterone has been demonstrated to reduce the risk of preterm birth. Conclusion Strategies including cervical length screening, vaginal progesterone administration, cervical cerclage placement, and, potentially, 17-P administration may help reduce rates of preterm birth when used in the appropriate patient populations. Development of protocols for patient evaluation and risk stratification will help identify patients at highest risk for preterm birth and allow use o