https://www.selleckchem.com/
Cells sense the biophysical cues in the microenvironment and respond to the cues biochemically and biophysically. Proper responses from the cells are critical to maintain the homeostasis in the body. The abnormal biophysical cues will cause pathological development in the cells; the pathological or aging cells, on the other hand, can alter the microenvironment to become abnormal. In this mini-review, we discuss four important biophysical cues of the microenvironment - stiffness, curvature, ECM architecture and viscosity - in terms of their roles in health,