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But, the fat-reducing mechanism of it stays uncertain. Making use of Caenorhabditis elegans (C. elegans) as a model, we found that C. paliurus polysaccharide (CPP) dramatically decreased fat storage space both in normal and high-fat worms without influencing the movement. More over, the size and amount of lipid droplets were low in CPP-treated ZXW618 worms. In energy kcalorie burning, CPP reduced Escherichia coli (E. coli) OP50 growth and pharyngeal pumping and enhanced the app