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We retrospectively evaluated 48 tumors in 46 clients from 11 institutions with a histologically confirmed diagnosis of LNET, treated with main radiotherapy. Data had been collected for patients addressed nonoperatively with main radiotherapy between 2006 and 2020. Individual files were assessed for lesion characteristics and medical risk elements. Kaplan-Meier analysis, log-rank examinations, and Cox multivariate designs were utilized to compare results. WNT signaling is a cellular path