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To evaluate the specificity of the expression patterns of microRNAs (miRNAs) in circulating CD4 T cells in aged patients with atherosclerosis obliterans (ASO). A comprehensive miRNA expression study was conducted using a miRNA microarray of CD4 T cells isolated from peripheral blood mononuclear cells (PBMCs) of 33 patients with ASO and 24 healthy donors. A t test was used for statistical analysis, and the average linkage method was used for hierarchical clustering. The results were validated by qRT-PCR. Putative targeted pathways associ
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