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325, P less then 0.038; small PVA less then small EM, χ2 = 6.68, P less then 0.01). Conclusion Both PVA and EM could occlude vessels smaller than the particle size, and EM resulted in deeper penetration. The location of embolic particles in the artery is mainly related to the shape of particles.Background Developing the natural medicine that allow for the specific targeting cytotoxicity is a very important research area in the development of anti-tumor drugs. Aims and objectives This study was conducted to determine the targeted inhibi