https://www.selleckchem.com/pr....oducts/tucidinostat-
The validated method was successfully applied to a preclinical pharmacokinetic study in Sprague-Dawley rats. IMB-YH-4py5-2H demonstrated improved pharmacokinetic properties (higher exposure level) compared with its leading compound. IMB-YH-4py5-2H was also distributed throughout the lung pronouncedly, especially inside alveolar macrophages, indicating its effectiveness against lower respiratory infections.[This corrects the article DOI 10.1371/journal.pone.0098077.].BACKGROUND We sought to assess the relative effects of i
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