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Treatment For ADHD The main treatments for add are medication and psychosocial therapy (psychotherapy). The medications contain stimulants such as methylphenidate, amphetamine and atomoxetine. They also include non-stimulants, such as clonidine and guanfacine. Stimulant medications should not be used in patients with active substance abuse problems but they are a possibility for those who are in stable in remission. Combination therapy with antidepressants (particularly SSRIs) is also an