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ADHD Treatment For Adults The stimulants like methylphenidate amphetamine, and other brain chemicals can help increase levels. Non-stimulants like atomoxetine, antidepressants, or are slower than stimulants, however, they can be as effective. Complicating conditions often affect the response to ADHD medication. The most severe symptom from any comorbid condition should be treated first. Then, the doctor should monitor whether ADHD symptoms imp