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531). EGFR mutation status (same mutations, different mutations, all wild-type) had no statistically significant effect on DFS of SMFLC ( =0.388). Univariate and multivariate regression analysis revealed that radiographic feature of solid nodules (hazard ratio ( )=7.4, =0.008) and MMFLC ( =5.6, =0.001) were independent risk factors for poor prognosis. MFLC can achieve a favorable prognosis with early surgical treatment. Tumor density and metachronous lesions are two important prognostic predictors. MFLC can achieve a favorable prognosis