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Also, in comparison to GAL-CSE4 which exhibits Synthetic Dosage Lethality (SDL) in psh1∆, slx5∆, and hir2∆ strains, GAL-cse4 K215/216R will not exhibit SDL within these strains. Taken together, our outcomes show that deposition of Cse4 into chromatin is facilitated by its C-terminal sumoylation. Copyright © 2020, Genetics.The nematode Caenorhabditis elegans is just one of the crucial model systems in biology, including possessing the very first totally put together animal genome. Wherea