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Although Nexplanon is one of the most effective and most utilized long-acting reversible contraceptives in Ghana. We report a rare event of Nexplanon failure in a woman with human immunodeficiency virus (HIV) infection in rural Ghana.Anaphylaxis due to prick-by-prick testing is a rare but potentially life-threatening complication. Personnel performing testing should be able to recognize and treat anaphylaxis. Adrenaline must be available. In high-risk patients with a history of anaphylaxis, specific igE with components and a basophile ac