https://vpainhibitor.com/usefu....l-qualities-plastici
Herein, we detail the total synthesis of cathelicidin-PY using a totally on-resin synthesis, including system regarding the linear sequence by rapid flow Fmoc-SPPS and iodine-mediated disulfide bridge formation. By optimising a synthetic technique to prepare cathelicidin-PY, this strategy ended up being later adapted to get ready a bicyclic head-to-tail cyclised derivative of cathelicidin-PY. The structure-activity relationship (SAR) of cathelicidin-PY according to the N-termin