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The present study suggests that investigation of GJB2 mutations may still be useful to determine the etiology of HL in Iran. 2020, International Research and Cooperation Association for Bio Socio - Sciences Advancement.TXNDC5 is an endoplasmic reticulum (ER)-resident chaperone that protects the endothelium from secondary effects of ER stress. Previous studies by the current authors identified TXNDC5 as a key pathological factor in promoting the inflammatory phenotype of fibroblast-like synoviocytes (FLSs) from rheumatoid arthritis
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