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by incorporating the efficient end-to-end CNN mapping, adversarial learning, and physical model enforced data consistency is a promising approach for rapid and efficient reconstruction of quantitative MR parameters. The products of the lysine biosynthesis pathway, meso-diaminopimelate and lysine, are essential for bacterial survival. This paper focuses on the structural and mechanistic characterization of 4-hydroxy-tetrahydrodipicolinate reductase (Dap, which is one of the enzymes from the lysine biosynthesis pathway. DapB catalyzes t