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The HPLC-MS/MS technique is a well balanced and painful and sensitive quantitative way for the determination of E-ZOP in biological matrices.Introduction Pheochromocytomas are unusual neuroendocrine tumors that form in chromaffin cells associated with the neural crest during the embryological duration. When you look at the general populace, occurrence price is 0.1%; not enough very early diagnosis or adequate therapy can lead to deadly complications. The secretion of catecholamines,